Garfield and Friends is an American animated television series based on the comic strip Garfield by Jim Davis. The show aired on CBS as part of its Saturday morning children's lineup from September 17, 1988, to December 10, 1994.

The show features animated story lines adapted from the comic strip Garfield and Davis's other comic strip U.S. Acres. Mark Evanier was the show's head writer. Lorenzo Music provided the voice of Garfield the cat, the strip's title character, as he had done since Here Comes Garfield in 1982. Other voices present on the show included Thom Huge as Jon Arbuckle, Garfield's human owner, and Gregg Berger as Odie the dog, also returning from prior Garfield animated media. Berger and Huge also respectively voiced Orson Pig and Roy Rooster in the U.S. Acres segments. 121 episodes were made, each consisting of two Garfield segments and one U.S. Acres segment and a "Garfield Quickie" at the end. All episodes have been released in the U.S. on five DVD sets by 20th Century Fox Home Entertainment.

The rights to the series are currently owned by Paramount Global as a result of its acquisition of Paws, Inc. on August 6, 2019. However, 9 Story Media Group currently distributes the show under license from Paramount.